Author

Mariana Rangel Pereira

University of Cambridge

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Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:proteomics· 1 Organism:yeast· 1

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Florian HollfelderiD· 1 shared Lutz JermutusiD· 1 shared Marko HyvöneniD· 1 shared P. BreariD· 1 shared Philipp KnyphauseniD· 1 shared

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Florian HollfelderORCID

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1 paper

Recent·Most cited

Synthetic BiologyNature CommunicationsPeer-reviewedFeb 10, 2023

Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture

Philipp Knyphausen, Mariana Rangel Pereira, P. Brear…·Florian Hollfelder

This paper introduces a method to evolve protease activity and specificity using yeast display and alpha-2-macroglobulin-mediated covalent capture, demonstrating its application on six serine proteases.

13 citations

yeastproteomics

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