Author
AstraZeneca (United Kingdom)ORCID 0000-0001-7660-8467Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Tom Pieper, Tobias Riët, Valerie Saetzler…·Elmar Jaeckel
This paper develops ENTPD3-specific CAR Tregs to control T1D by targeting beta cells and shows their efficacy in preventing disease progression in a mouse model.
Philipp Knyphausen, Mariana Rangel Pereira, P. Brear…·Florian Hollfelder
This paper introduces a method to evolve protease activity and specificity using yeast display and alpha-2-macroglobulin-mediated covalent capture, demonstrating its application on six serine proteases.
Yanislava Karusheva, Matthew Ratcliff, Alexander Mörseburg…·Stephen O’Rahilly
The study shows that the H202D variant in GDF-15 does not affect its bioactivity but causes underreporting in R&D immunoassays, with correction equations provided.