Author

Marie S. Roberts

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

Hemanth R. NelvagaliD· 2 shared Jonathan D. CooperiD· 2 shared Mark S. SandsiD· 2 shared Patricia DicksoniD· 2 shared Steven Q. LeiD· 2 shared Alexander Sorensen· 1 shared Balraj DorayiD· 1 shared Bethann N. ValentineiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Hemanth R. NelvagalORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GABAergic interneurons contribute to the fatal seizure phenotype of CLN2 disease mice

Keigo Takahashi, Nicholas R. Rensing, Elizabeth M. Eultgen, Letitia L. Williams, Sophie H. Wang, Hemanth R. Nelvagal, Steven Q. Le, Marie S. Roberts, Balraj Doray, Edward B. Han, Patricia Dickson, Michael Wong, Mark S. Sands, Jonathan D. Cooper

This study investigates the role of GABAergic interneurons in seizure progression and mortality in CLN2 disease mice, finding that interneuron dysfunction contributes to epileptic seizures and death.

JCI Insight · Aug 21, 2025Peer-reviewedNeuroscience

Recombinant NAGLU-IGF2 prevents physical and neurological disease and improves survival in Sanfilippo B syndrome

Steven Q. Le, Shih‐hsin Kan, Marie S. Roberts, Joshua T. Dearborn, Feng Wang, Shan Li, Elizabeth M. Snella, Jackie K. Jens, Bethann N. Valentine, Hemanth R. Nelvagal, Alexander Sorensen, Keerthana Chintalapati, Kevin K. Ohlemiller, Carole A. Vogler, Jonathan D. Cooper, , Patricia Dickson

This study shows that rhNAGLU-IGF2 treatment improves disease markers, behavior, and survival in Sanfilippo B mice and dogs.

bioRxiv · Aug 6, 2021 · PreprintNeuroscience