Author
Université Laval
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Bac Viet Le, Umeshkumar M. Vekariya, Monika Maria Toma…·Tomasz Skórski
This study identifies Polθ as a therapeutic target in DNMT3A-mutated leukemia by showing its essential role in DNA repair and replication fork restart, and demonstrates that its inhibition enhances standard therapies.
Kärt Mätlik, Matthew Baffuto, Laura Kus…·Nathaniel Heintz
The paper investigates CAG repeat expansions and their association with cell death in specific brain regions in Huntington's disease using molecular profiling.
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic…·Christopher E. Pearson
The paper investigates the roles of canonical and alternative RPA in CAG repeat diseases, finding that Alt-RPA antagonizes RPA's suppression of CAG expansions, contributing to disease pathogenesis.
Amit Laxmikant Deshmukh, Marie‐Christine Caron, Mohiuddin Mohiuddin…·Christopher E. Pearson
The paper shows FAN1 nuclease processes and pauses on slipped-DNA repeats, reducing repeat expansions and delaying disease onset.
Abhishek Bharadwaj Sharma, Hélène Erasimus, Lia Pinto…·Eric Van Dyck