Author
Temple UniversityORCID 0000-0001-8414-253XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Madison A. Lineberger, Zach H. Gray, Benjamin I. Ferman…·Johnathan R. Whetstine
The paper identifies a DNA-histone methylation axis that drives KMT2A amplifications and rearrangements in leukemia, revealing therapeutic targets.
Bac Viet Le, Umeshkumar M. Vekariya, Monika Maria Toma…·Tomasz Skórski
This study identifies Polθ as a therapeutic target in DNMT3A-mutated leukemia by showing its essential role in DNA repair and replication fork restart, and demonstrates that its inhibition enhances standard therapies.
V.S.S. Abhinav Ayyadevara, Shikha Gaur, Ashley Paik…·Christian Hurtz
This study identifies BRG1 as a critical target in Ph-like B-ALL, showing its inhibition leads to cell cycle arrest and improved survival in preclinical models.