Author

Umeshkumar M. Vekariya

Temple UniversityORCID 0000-0002-6662-9122Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Alfonso BellacosaiD· 1 shared Anna-Mariya Kukuyan· 1 shared Bac Viet LeiD· 1 shared Brian J.P. HuntlyiD· 1 shared Elaine Vaughan‐Williams· 1 shared Emir HadzijusufoviciD· 1 shared Gaorav P. GuptaiD· 1 shared George S. VassiliouiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alfonso BellacosaORCID

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1 paper

Recent·Most cited

Cancer BiologyCell Reports MedicinePeer-reviewedMar 1, 2026

Pol is a functional dependency and therapeutic vulnerability in DNMT3A deficient leukemia cells

Bac Viet Le, Umeshkumar M. Vekariya, Monika Maria Toma…·Tomasz Skórski

This study identifies Polθ as a therapeutic target in DNMT3A-mutated leukemia by showing its essential role in DNA repair and replication fork restart, and demonstrates that its inhibition enhances standard therapies.

1 citation

humanDNA methylation

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