Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress
Benjamin Boumard, Gwenn Le Meur, Marine Stefanutti, Tania Maalouf, Marwa El-Hajj, Reinhard Bauer, Allison J. Bardin
The paper shows that gap junctions enable nucleotide sharing between cells, buffering replication stress and affecting cell sensitivity to dNTP depletion.
bioRxiv · Aug 15, 2023 · PreprintDevelopmental Biology