Developmental BiologybioRxivPreprint
Molecular Underpinnings and Environmental Drivers of Spontaneous Loss of Heterozygosity in Drosophila Intestinal Stem Cells
Lara Al Zouabi, Marine Stefanutti, Nick Riddiford…·Allison J. Bardin
This study identifies mitotic recombination as the primary mechanism for loss of heterozygosity in Drosophila intestinal stem cells, showing increased LOH frequency with specific bacterial infection.