Author

Marisol Cano

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

James T. HandaiD· 3 shared Debasish SinhaiD· 2 shared Jiang X. QianiD· 2 shared Seth BlackshawiD· 2 shared Thanh V. HoangiD· 2 shared Andrew E. JaffeiD· 1 shared Cristina ZibettiiD· 1 shared Daianna González‐PadillaiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

James T. HandaORCID

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3 papers

Recent·Most cited

Molecular impact of nicotine and smoking exposure on the developing and adult mouse brain

Daianna González‐Padilla, Nicholas J. Eagles, Marisol Cano, Geo Pertea, Andrew E. Jaffe, Kristen R. Maynard, Dana B. Hancock, James T. Handa, Keri Martinowich, Leonardo Collado‐Torres

This study compares the molecular effects of prenatal nicotine exposure and maternal smoking during pregnancy on mouse brain development and adulthood, finding distinct gene expression changes in pups but not adults.

Addiction Neuroscience · Jul 15, 2026Peer-reviewedNeuroscience

Cigarette smoke and biological age induce degenerative heterogeneity in retinalpigment epithelium

Krishna Singh, Yang Oh Jin, Ming-Wen Hu, Isabella Palazzo, Marisol Cano, Thanh V. Hoang, Imran Ahmed Bhutto, Shusheng Wang, Debasish Sinha, Seth Blackshaw, Jiang X. Qian, James T. Handa

This study shows cigarette smoke and aging induce degenerative heterogeneity in RPE cells through distinct epigenetic changes, with young RPE showing compensatory responses not seen in aged RPE.

bioRxiv · Jan 27, 2025 · PreprintNeuroscience

A widespread decrease of chromatin accessibility in age-related macular degeneration

Jie Wang, Cristina Zibetti, Peng Shang, Srinivas R. Sripathi, Pingwu Zhang, Marisol Cano, Thanh V. Hoang, Shuli Xia, Hongkai Ji, Shannath L. Merbs, Donald J. Zack, James T. Handa, Debasish Sinha, Seth Blackshaw, Jiang X. Qian

This study identifies global decreases in chromatin accessibility in AMD patients, linking epigenetic changes to disease progression and suggesting HDAC11 as a potential therapeutic target.

Nature Communications · Apr 4, 2018Peer-reviewedGenomics