Reprogramming method does not impact the neuronal differentiation potential of 16p11.2 deletion patient iPSCs
Michael F. Wells, Ellen J. Guss, Hongyan Zhou, Bruce Qiang Sun, Héctor Martínez, The NYSCF Global Stem Cell Array Team, Veronika Akopian, Scott Noggle, Daniel J Paull, Jennifer C. Moore, Michael Sheldon, Julia E. Sommer, Marta Benedetti, Alexander Meissner, Kevin C. Eggan
The study compares reprogramming methods for 16p11.2 deletion patient iPSCs and finds no significant differences in their differentiation potential into functional neurons.
bioRxiv · Jul 7, 2023 · PreprintDevelopmental Biology