Ellen J. Guss

Reprogramming method does not impact the neuronal differentiation potential of 16p11.2 deletion patient iPSCs

The study compares reprogramming methods for 16p11.2 deletion patient iPSCs and finds no significant differences in their differentiation potential into functional neurons.

Loss of the extracellular matrix protein Perlecan disrupts axonal and synaptic stability during Drosophila development

This study shows that Perlecan is essential for maintaining axonal and synaptic stability in Drosophila motoneurons, with its loss causing axonal breakage and synaptic retraction.

The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia

This study investigates how the 22q11.2 deletion affects gene expression in neural progenitor cells and neurons, linking it to schizophrenia risk through altered presynaptic gene products.

Genome-wide screens in accelerated human stem cell-derived neural progenitor cells identify Zika virus host factors and drivers of proliferation