Jennifer C. Moore

The study compares reprogramming methods for 16p11.2 deletion patient iPSCs and finds no significant differences in their differentiation potential into functional neurons.

This study validates that heterozygous NRXN1 deletions impair neurotransmitter release in human neurons across multiple labs, suggesting a human-specific synaptic dysfunction relevant for schizophrenia drug discovery.

This study examines how the N40D variant of the mu-opioid receptor affects synaptic function in human neurons, showing variant-specific effects on inhibitory transmission.