Author

Marta Botas

Consorci Institut D'Investigacions Biomediques August Pi I Sunyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alba Rodríguez-GarcíaiD· 1 shared Aleix PratiD· 1 shared Álvaro Urbano-IspizúaiD· 1 shared Anna Esteve‐CodinaiD· 1 shared Ariel Galindo‐AlbarrániD· 1 shared Beatriz Martín-MuriD· 1 shared Berta MarzaliD· 1 shared Guillem Colell· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alba Rodríguez-GarcíaORCID

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1 paper

Recent·Most cited

In vivo CRISPR-based screen identifies ZC3H12C as a mediator of CAR-T cell dysfunction in solid tumors

Paula Barbao, Alba Rodríguez-García, Ariel Galindo‐Albarrán, Marta Giménez-Alejandre, Pablo Clavero, Teresa Lobo‐Jarne, Marta Botas, Guillem Colell, Joan Castellsagué, Guim Cascalló, Irene Andreu-Saumell, Marta Soria-Castellano, Salut Colell, Berta Marzal, Beatriz Martín-Mur, , Sònia Guedan

The paper identifies ZC3H12C as a mediator of CAR-T cell dysfunction in solid tumors through an in vivo CRISPR screen and validates its role using single-cell RNA and ATAC-seq.

bioRxiv · May 2, 2026 · PreprintImmunology