NeurosciencebioRxivPreprint
Targeting CDC42 with CASIN Reprograms Cell-Type-Specific Transcriptomes and MAPK-Driven Transcription Factor Networks in the Aging Brain
Jaehyun LeeBae, Verena Bopp, Bettina Moehrle…·Karin M. Danzer
The paper shows that CASIN inhibits CDC42, reversing PD-related transcriptional changes and affecting MAPK and PI3K/AKT pathways in an aging mouse model.