Author

Matt Sears

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Cameron ParroiD· 1 shared Chinnakkaruppan AdaikkaniD· 1 shared Karim AbdelaaliD· 1 shared Li‐Huei TsaiiD· 1 shared M KellisiD· 1 shared Mia Sedgwick· 1 shared Na SuniD· 1 shared P. Lorenzo BozzelliiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Cameron ParroORCID

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1 paper

Recent·Most cited

A multimodal approach of microglial CSF1R inhibition and GENUS provides therapeutic effects in Alzheimers disease mice

Chinnakkaruppan Adaikkan, Rezaul Islam, P. Lorenzo Bozzelli, Matt Sears, Cameron Parro, Ping‐Chieh Pao, Na Sun, TaeHyun Kim, Karim Abdelaal, Mia Sedgwick, M Kellis, Li‐Huei Tsai

The paper shows that combining CSF1R inhibition with GENUS stimulation improves cognitive function in Alzheimer's mice by restoring neural circuitry and gene expression.

bioRxiv · Apr 27, 2025 · PreprintNeuroscience