Chronic oral fentanyl consumption produces dynamic behavioral adaptations during abstinence in female mice
Mengfan Xia, Brianna E. George, Maximilian Caza, Jobe L. Ritchie, Thomas L. Kash
This study examines behavioral adaptations in female mice during fentanyl abstinence, finding persistent withdrawal symptoms and altered behaviors that may contribute to relapse vulnerability.
bioRxiv · Jul 30, 2026 · PreprintNeuroscience