Author

Maykel Lopes

University of Lausanne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:statistical model· 2 Organism:yeast· 2 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Amandine BattéiD· 2 shared Carles PonsiD· 2 shared Gianni LitiiD· 2 shared Jolanda S. van LeeuweniD· 2 shared Leopold PartsiD· 2 shared Patrick AloyiD· 2 shared Andrei ChabesiD· 1 shared Bryan-Joseph San Luis· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenomics

Amandine BattéORCID

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2 papers

Recent·Most cited

The modifiers that cause changes in gene essentiality

Amandine Batté, Núria Bosch-Guiteras, Carles Pons, Marina Ota, Maykel Lopes, Sushma Sharma, Nicolò Tellini, Claire Paltenghi, Michelle M. Conti, Kwan Ting Kan, Uyen Linh Ho, Michaël Wiederkehr, J. -F. Barraud, Mark Ashe, Patrick Aloy, , Jolanda S. van Leeuwen

The paper identifies suppressor variants that alter gene essentiality across yeast strains, revealing context-dependent genetic mechanisms.

Cell Systems · Mar 2, 2026Peer-reviewedGenomics

Diverse natural variants suppress mutations in hundreds of essential genes

Leopold Parts, Amandine Batté, Maykel Lopes, Michael Wai-Keong Yuen, Meredith Laver, Bryan-Joseph San Luis, Jia‐Xing Yue, Carles Pons, Elise Eray, Patrick Aloy, Gianni Liti, Jolanda S. van Leeuwen

The paper measures how natural genetic variation can suppress mutations in essential yeast genes, finding that 35% of tested genes can be suppressed by modifier genes in different backgrounds.

Molecular Systems Biology · May 1, 2021Peer-reviewedGenetics