Author

Bryan-Joseph San Luis

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:yeast· 3 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:genome assembly· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Charles M. BooneiD· 2 shared Christopher J. BrandliD· 2 shared Grant W. BrowniD· 2 shared Judit VilléniD· 2 shared Julie L. Genereaux· 2 shared Matthew D. BergiD· 2 shared Raphaël Loll‐KrippleberiD· 2 shared Yanrui Zhu· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMolecular Biology

Charles M. BooneORCID

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Author profile →

3 papers

Recent·Most cited

Genetic background and mistranslation frequency determine the impact of mistranslating tRNASerUGG

Matthew D. Berg, Yanrui Zhu, Raphaël Loll‐Krippleber, Bryan-Joseph San Luis, Julie L. Genereaux, Charles M. Boone, Judit Villén, Grant W. Brown, Christopher J. Brandl

This study shows that the impact of a mistranslating tRNA variant depends on genetic background and mistranslation frequency in yeast, with implications for understanding tRNA variants in human disease.

G3 Genes Genomes Genetics · May 19, 2022Peer-reviewedMolecular Biology

The amino acid substitution affects cellular response to mistranslation

Matthew D. Berg, Yanrui Zhu, Bianca Y. Ruiz, Raphaël Loll‐Krippleber, Joshua Isaacson, Bryan-Joseph San Luis, Julie L. Genereaux, Charles M. Boone, Judit Villén, Grant W. Brown, Christopher J. Brandl

This study compares the effects of two tRNA variants causing different amino acid substitutions in yeast, showing distinct impacts on growth, heat shock response, and transcriptome changes.

G3 Genes Genomes Genetics · Jun 26, 2021Peer-reviewedMolecular Biology

Diverse natural variants suppress mutations in hundreds of essential genes

Leopold Parts, Amandine Batté, Maykel Lopes, Michael Wai-Keong Yuen, Meredith Laver, Bryan-Joseph San Luis, Jia‐Xing Yue, Carles Pons, Elise Eray, Patrick Aloy, Gianni Liti, Jolanda S. van Leeuwen

The paper measures how natural genetic variation can suppress mutations in essential yeast genes, finding that 35% of tested genes can be suppressed by modifier genes in different backgrounds.

Molecular Systems Biology · May 1, 2021Peer-reviewedGenetics