Author

Mayra Marquez

Frederick National Laboratory for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Tomozumi ImamichiiD· 2 shared Udeshika KariyawasamiD· 2 shared Adam Ruppert· 1 shared Hongyan SuiiD· 1 shared Jordan B. MetziD· 1 shared Ju Qu· 1 shared Jun Yang· 1 shared Jun YangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Tomozumi ImamichiORCID

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2 papers

Recent·Most cited

IL-27 Reduces Cell-Surface LDLR in Human Macrophages and Restricts VSV-G-Pseudotyped HIV infection

Qian Chen, Udeshika Kariyawasam, Mayra Marquez, Jordan B. Metz, Jun Yang, Adam Ruppert, Tomozumi Imamichi

This study shows IL-27 reduces cell-surface LDLR in macrophages and limits VSV-G-pseudotyped HIV infection through receptor downregulation and post-entry mechanisms.

bioRxiv · Oct 28, 2026 · PreprintImmunology

Beyond Metabolism: Pyruvate Carboxylase Acts as a Sequence-Selective Small RNA Sensor Orchestrating Antiviral Responses

Udeshika Kariyawasam, Suranjana Goswami, Ming Hao, Rosana Wiscovitch-Russo, Q Chen, Jun Yang, Ju Qu, Mayra Marquez, Hongyan Sui, Weizhong Chang, Tomozumi Imamichi

The paper shows miRTC14 activates IFN expression through interaction with pyruvate carboxylase and LGP2, leading to TBK1 phosphorylation and IFN subtype production.

bioRxiv · Aug 5, 2026 · PreprintImmunology