Diverse Plant-Parasitic Nematodes are Selectively Killed by Oxadiazole Thioether Pro-Nematicides
Jessica J. Knox, Andrew R. Burns, Brittany Cooke, Savina R. Cammalleri, Megan Kitner, Justin Ching, Jack M.P. Castelli, Emily Puumala, Jamie D. Snider, Emily J. Koury, J.B. Collins, Erik C. Andersen, Igor Štagljar, Leah E. Cowen, Mark Lautens, , Peter John Roy
The paper discovers a pro-nematicide scaffold, Cyprocide, that selectively kills diverse plant-parasitic nematodes through P450 enzyme activation, offering a potential solution for sustainable nematode management.
bioRxiv · Sep 14, 2023 · PreprintGenetics