J.B. Collins

The paper identifies beta-tubulin variants associated with benzimidazole resistance in three Caenorhabditis species and shows species-specific patterns of resistance.

The paper identifies 94 candidate genes in C. elegans linked to susceptibility to 23 environmental toxicants using genome-wide association analysis.

This study tests fenbendazole efficacy against ascarid parasites in poultry, finding resistance in one Ascaridia galli isolate and all Heterakis gallinarum isolates.

This paper develops a mesh filter-based technique to isolate C. elegans embryos for synchronization, achieving higher yield and better downstream development than bleach methods.

This paper identifies a cytochrome P450 gene variant that contributes to benzimidazole resistance in nematodes, independent of beta-tubulin mutations.

This study quantifies the fitness effects of resistance alleles to albendazole and ivermectin in C. elegans, finding that resistance requires specific gene deletions and that multi-drug resistance is not observed.

The paper identifies a new TA system in C. elegans with divergent toxin alleles suppressed by distinct mechanisms, including piRNA-mediated silencing in the N2 haplotype.

The paper tests the role of five beta-tubulin genes in benzimidazole resistance in C. elegans, finding that only ben-1 loss confers substantial resistance.

The paper discovers a pro-nematicide scaffold, Cyprocide, that selectively kills diverse plant-parasitic nematodes through P450 enzyme activation, offering a potential solution for sustainable nematode management.

This paper identifies widespread benzimidazole resistance in Ancylostoma caninum from dogs across the USA, including a novel β-tubulin mutation and confirms its functional significance.

The paper evaluates DNA extraction methods for whole genome sequencing of individual helminth eggs and larvae, showing successful sequencing for six of eight species tested.