Author

Megan R Torgrimson

University of California, Santa Cruz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Carrie L. PartchiD· 2 shared Alfred M. FreebergiD· 1 shared Alicia K. MichaeliD· 1 shared Chelsea L. Gustafson· 1 shared Clarisse Gravina RicciiD· 1 shared David M. VirshupiD· 1 shared Diksha SharmaiD· 1 shared Emilia Pecora de BarrosiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Carrie L. PartchORCID

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2 papers

Recent·Most cited

BiophysicsBiophysical JournalPeer-reviewedSep 18, 2025

Markovian State Models uncover Casein Kinase 1 dynamics that govern circadian period

Clarisse Gravina Ricci, Jonathan M. Philpott, Megan R Torgrimson…·Carrie L. Partch

This paper uses molecular dynamics simulations and Markovian State Models to analyze CK1 conformational dynamics, revealing how the tau mutant alters substrate selectivity and affects circadian period.

3 citations

structural biologydeep learning

𝕏 PostBluesky

BiophysicsbioRxivPreprintSep 4, 2025

Tandem association of CLOCK:BMAL1 complexes on DNA enables recruitment of CBP/p300 through multivalent interactions

Diksha Sharma, Lisa Stoos, Megan R Torgrimson…·Carrie L. Partch

The paper shows that tandem E-boxes enable CLOCK:BMAL1 to bind more sites on nucleosomes, promoting multivalent interactions with CBP/p300 to drive gene expression.

2 citations

DNA methylationChIP-seq

𝕏 PostBluesky