Author

Melanie Horn

University of Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:software / tool· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Fabian F. VoigtiD· 1 shared Fritjof HelmcheniD· 1 shared Joana Figueiro‐SilvaiD· 1 shared Kris VleminckxiD· 1 shared Nikita VladimiroviD· 1 shared Philipp BethgeiD· 1 shared Ruth RöckiD· 1 shared Ruxandra Bachmann‐GagescuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Fabian F. VoigtORCID

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1 paper

Recent·Most cited

Pythia: Non-random DNA repair allows predictable CRISPR/Cas9 integration and gene editing

Thomas Naert, Taiyo Yamamoto, Shuting Han, Ruth Röck, Melanie Horn, Philipp Bethge, Nikita Vladimirov, Fabian F. Voigt, Joana Figueiro‐Silva, Ruxandra Bachmann‐Gagescu, Kris Vleminckx, Fritjof Helmchen, Soeren S. Lienkamp

The paper introduces Pythia, a tool that uses deep learning to predict CRISPR/Cas9 integration and editing outcomes by leveraging non-random DNA repair patterns.

Nature Biotechnology · Aug 12, 2025Peer-reviewedMolecular Biology