Author

Melodie Chiu

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1

Frequent Co-Authors

David A. BakeriD· 2 shared Jay ShendureiD· 2 shared Aditya KrishnakumariD· 1 shared Alec S.T. SmithiD· 1 shared Alexander J. RobinsoniD· 1 shared Ashish PhaliD· 1 shared Chase C. SuiteriD· 1 shared David J. LeeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

David A. BakerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Designed Minibinders Rewire Receptor Signaling to Enable Functional Human Myogenic Reprogramming

Riya Keshri, Zachary Foreman, Philip Barrett, Alexander J. Robinson, Gabriela Reyes, Ashish Phal, Aditya Krishnakumar, Ethan Narog, Melodie Chiu, Shruti Jain, Xinru Wang, David J. Lee, Marc Expòsit, Mohamad H. Abedi, Alec S.T. Smith, , Hannele Ruohola‐Baker

This paper demonstrates that AI-designed receptor modulators can drive efficient human fibroblast-to-muscle transdifferentiation by rewiring extracellular signaling.

bioRxiv · Apr 27, 2026 · PreprintBiochemistry

Multiplex design and discovery of proximity handles for programmable proteome editing

Chase C. Suiter, Green Ahn, Melodie Chiu, Yi Fu, Shayan Sadre, Jessica J. Simon, David S. Lee, Douglas M. Fowler, Dustin J. Maly, David A. Baker, Jay Shendure

The paper develops a method to discover new effector handles for proteome editing by combining de novo protein design with multiplex screening, identifying handles for degradation and stabilization of target proteins.

bioRxiv · Oct 13, 2025 · PreprintSynthetic Biology