Lysosomal control of proteostasis and reproductive capacity by conserved LMD-3 protein in C. elegans
Yile Zhai, Tiantian Wang, Jiangxue Han, Mengxiao Wu, Meixi Gong, Wenfei Li, Zhe Zhang
This study identifies LMD-3 as a regulator of proteostasis and reproductive capacity in C. elegans, showing its role in lysosomal function and the reversibility of fecundity decline with vitamin B12.
Science Advances · Nov 26, 2025Peer-reviewedCell Biology