Wenfei Li

The paper isolates functional endogenous clathrin-coated vesicles and reconstitutes pure clathrin cages from porcine brain, free of lipid contaminants.

This study shows that the LMD-3 mutation in C. elegans causes reproductive failure by disrupting lysosomal function and proteostasis, which can be reversed with vitamin B12 supplementation.

This paper presents an optimized E. coli cell-free protein synthesis system with fewer components and a simplified protocol, improving efficiency and accessibility for protein synthesis.

This study identifies the Archaeal Ribosome regulatory Complex (ARC) as a dual-factor complex that modulates ribosome hibernation in response to energy status.

This study identifies the conserved NUS-1/DHDDS complex in C. elegans as essential for linking N-glycosylation to lipid and lysosomal homeostasis, revealing its role in preventing developmental failure and metabolic disorders.

This study identifies LMD-3 as a regulator of proteostasis and reproductive capacity in C. elegans, showing its role in lysosomal function and the reversibility of fecundity decline with vitamin B12.