Author

Meredith O. Kelly

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Gretchen A. MeyeriD· 2 shared Muhammad G. Mousa· 2 shared Rita T. BrookheartiD· 2 shared Shelby Ek· 2 shared Ana Navas‐AciéniD· 1 shared Anum Glasgow· 1 shared Brian N. FinckiD· 1 shared Cong LiuiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Gretchen A. MeyerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Manganese availability determines insulin sensitivity by enhancing Akt activity

Jennifer R. Gamarra, Sei Higuchi, Timothy L. Yuan, YUKE XIE, Cong Liu, Niroshan Shanmugarajah, Hang Yang, Meredith O. Kelly, Sarah Anissa Hannou, Kathrin Schilling, Ana Navas‐Acién, Eunhee Choi, Anum Glasgow, Inna I. Astapova, Mark A. Herman, Rebecca A. Haeusler

This study identifies manganese as a regulator of Akt activity independent of PI3K, showing it enhances Akt catalytic efficiency and interacts with insulin to modulate glucose homeostasis.

bioRxiv · Sep 17, 2026 · PreprintPhysiology

Site-1 Protease is a negative regulator of sarcolipin promoter activity

Isha Sharma, Meredith O. Kelly, Katelyn Hanners, Ella S. Shin, Muhammad G. Mousa, Shelby Ek, Gretchen A. Meyer, Rita T. Brookheart

This study shows that Site-1 Protease (S1P) negatively regulates sarcolipin expression by inhibiting its promoter activity through ATF6 and CREB binding.

Communications Biology · Sep 24, 2025Peer-reviewedMolecular Biology

Site-1 Protease inhibits mitochondrial metabolism by controlling the TGF-β target gene MSS51

Muhammad G. Mousa, Lahari Vuppaladhadiam, Meredith O. Kelly, Terri Pietka, Shelby Ek, Karen C. Shen, Gretchen A. Meyer, Brian N. Finck, Rita T. Brookheart

This study identifies Site-1 Protease (S1P) as a negative regulator of muscle mass and mitochondrial metabolism by controlling the TGF-β target gene MSS51.

Cell Reports · Mar 31, 2023Peer-reviewedMolecular Biology