Age-related changes in Tau and Autophagy in human brain in the absence of neurodegeneration
Shreyasi Chatterjee, Megan A. Sealey, Eva Ruiz, Chrysia M. Pegasiou, Keeley J. Brookes, Sam Green, Anna Crisford, Michael Duque-Vasquez, Emma Susanne Luckett, Rebecca Robertson, Philippa Richardson, Girish Vajramani, Paul Grundy, Diederik Olivier Bulters, Christopher G. Proud, , Amritpal K. Mudher
The paper examines age-related changes in tau and autophagy in cognitively normal individuals without neurodegeneration, finding reduced soluble tau and potential autophagy involvement.
PLoS ONE · Jan 26, 2023Peer-reviewedNeuroscience