Eva Ruiz

This study shows that Tau aggregation, not phosphorylation, is critical for neurotoxicity in Drosophila, suggesting that targeting aggregation may be more effective than targeting phosphorylation in tauopathies.

This study shows that activating the WldS pathway can prevent tau-mediated axonal degeneration in a Drosophila model, even when initiated after degeneration has started.

The paper examines age-related changes in tau and autophagy in cognitively normal individuals without neurodegeneration, finding reduced soluble tau and potential autophagy involvement.