Author

Girish Vajramani

University Hospital Southampton NHS Foundation TrustORCID 0000-0002-6079-6640Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Chrysia M. Pegasiou· 2 shared Diederik Olivier BultersiD· 2 shared Mariana Vargas‐CaballeroiD· 2 shared Paul Grundy· 2 shared Aminul Islam AhmediD· 1 shared Amritpal K. MudheriD· 1 shared Anna CrisfordiD· 1 shared Ardalan H ZolnourianiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Chrysia M. Pegasiou

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2 papers

Recent·Most cited

Age-related changes in Tau and Autophagy in human brain in the absence of neurodegeneration

Shreyasi Chatterjee, Megan A. Sealey, Eva Ruiz, Chrysia M. Pegasiou, Keeley J. Brookes, Sam Green, Anna Crisford, Michael Duque-Vasquez, Emma Susanne Luckett, Rebecca Robertson, Philippa Richardson, Girish Vajramani, Paul Grundy, Diederik Olivier Bulters, Christopher G. Proud, , Amritpal K. Mudher

The paper examines age-related changes in tau and autophagy in cognitively normal individuals without neurodegeneration, finding reduced soluble tau and potential autophagy involvement.

PLoS ONE · Jan 26, 2023Peer-reviewedNeuroscience

Age dependent changes in synaptic NMDA receptor composition in adult human cortical neurons

Chrysia M. Pegasiou, Ardalan H Zolnourian, Diego Gómez‐Nicola, Katrin Deinhardt, James A. R. Nicoll, Aminul Islam Ahmed, Girish Vajramani, Paul Grundy, Matthijs B Verhoog, Huibert D. Mansvelder, Victor Hugh Perry, Diederik Olivier Bulters, Mariana Vargas‐Caballero

The paper shows an age-dependent decline in GluN2B-containing NMDA receptors in human cortical synapses, potentially contributing to age-related cognitive decline.

Cerebral Cortex · Feb 28, 2020Peer-reviewedNeuroscience