Author

Megan A. Sealey

University of Southampton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Drosophila· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Amritpal K. MudheriD· 2 shared Eva RuiziD· 2 shared Anna CrisfordiD· 1 shared B.G. BatcheloriD· 1 shared Brad Richardson· 1 shared Christopher G. ProudiD· 1 shared Chrysia M. Pegasiou· 1 shared Diederik Olivier BultersiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Amritpal K. MudherORCID

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2 papers

Recent·Most cited

Tau-mediated axonal degeneration is prevented by activation of the WldS pathway

Katy Stubbs, B.G. Batchelor, Lovesha Sivanantharajah, Megan A. Sealey, Miguel Ramírez Moreno, Eva Ruiz, Brad Richardson, Victor Hugh Perry, Tracey A. Newman, Amritpal K. Mudher

This study shows that activating the WldS pathway can prevent tau-mediated axonal degeneration in a Drosophila model, even when initiated after degeneration has started.

Brain Communications · Mar 2, 2023Peer-reviewedNeuroscience

Age-related changes in Tau and Autophagy in human brain in the absence of neurodegeneration

Shreyasi Chatterjee, Megan A. Sealey, Eva Ruiz, Chrysia M. Pegasiou, Keeley J. Brookes, Sam Green, Anna Crisford, Michael Duque-Vasquez, Emma Susanne Luckett, Rebecca Robertson, Philippa Richardson, Girish Vajramani, Paul Grundy, Diederik Olivier Bulters, Christopher G. Proud, , Amritpal K. Mudher

The paper examines age-related changes in tau and autophagy in cognitively normal individuals without neurodegeneration, finding reduced soluble tau and potential autophagy involvement.

PLoS ONE · Jan 26, 2023Peer-reviewedNeuroscience