Author

Michael Piechotta

University Hospital Heidelberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:long-read sequencing· 3 Organism:human· 2 Research Focus:software / tool· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Christoph DieterichiD· 3 shared Isabel S. Naarmann‐de VriesiD· 2 shared Ann E. Ehrenhofer‐MurrayiD· 1 shared Arik ErmshausiD· 1 shared Bertil SchmidtiD· 1 shared Bhargesh Indravadan Patel· 1 shared Felix KallenborniD· 1 shared Francesca TuortoiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBioinformatics

Christoph DieterichORCID

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Author profile →

4 papers

Recent·Most cited

QutRNA2: Robust tRNA modification discovery from Nanopore direct tRNA sequencing

Michael Piechotta, Wei Guo, Isabel S. Naarmann‐de Vries, Felix Kallenborn, Swastik Mishra, Francesca Tuorto, Bertil Schmidt, Christoph Dieterich

QutRNA2 improves tRNA modification detection using Nanopore sequencing with GPU acceleration, achieving faster performance and identifying modifications in human and mouse tRNAs.

NAR Genomics and Bioinformatics · Jun 27, 2026Peer-reviewedBioinformatics

MoDorado: Enhanced detection of tRNA modifications in nanopore sequencing by off-label use of modification callers

Franziskus Hauth, Wang Liu-Wei, Yu Sun, Bhargesh Indravadan Patel, Wiep van der Toorn, Michael Piechotta, Christoph Dieterich, Max von Kleist, Ann E. Ehrenhofer‐Murray

The paper introduces MoDorado, an algorithm that detects tRNA modifications beyond those trained in existing models, identifying seven new modifications in S. pombe.

Nucleic Acids Research · Aug 1, 2025Peer-reviewedMolecular Biology

preon: Fast and accurate entity normalization for drug names and cancer types in precision oncology

Arik Ermshaus, Michael Piechotta, Gina Rüter, Ulrich Keilholz, Ulf Leser, Manuela Benary

preon normalizes drug names and cancer types in large-scale data for precision oncology.

Bioinformatics · Feb 20, 2024Peer-reviewedBioinformatics

RNA modification mapping with JACUSA2

Michael Piechotta, Isabel S. Naarmann‐de Vries, Qi Wang, Janine Altmüller, Christoph Dieterich

The paper introduces JACUSA2, a software framework for analyzing RNA modification data from multiple sequencing platforms and experimental conditions, demonstrating its use on m6A detection datasets.

Genome biology · May 16, 2022Peer-reviewedBioinformatics