Author

Michael Schnall-Levin

10X Genomics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genomics· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Research Focus:clustering· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

Rajiv Bharadwaj· 3 shared Bill K. Lin· 2 shared Christopher M. Hindson· 2 shared Claudia Catalanotti· 2 shared David A. StaffordiD· 2 shared Joe Shuga· 2 shared Kamila Belhocine· 2 shared Monkol LekiD· 2 shared

Activity by Year

2016-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersGenomics

Rajiv Bharadwaj

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4 papers

Recent·Most cited

Joint single cell DNA-Seq and RNA-Seq of gastric cancer reveals subclonal signatures of genomic instability and gene expression

Noemi Andor, Billy T. Lau, Claudia Catalanotti, Vijay Kumar, Anuja Sathe, Kamila Belhocine, Tobias D. Wheeler, Andrew D. Price, Maengseok Song, Željko Džakula, Jon M. Sorenson, David A. Stafford, Zachary Bent, Laura E. DeMare, Lance Hepler, , Hanlee P. Ji

The paper combines single cell DNA-Seq and RNA-Seq in gastric cancer to reveal subclonal genomic instability and gene expression patterns, showing evidence of tumor evolution.

bioRxiv · Jun 21, 2020 · PreprintGenomics

Resolving the Full Spectrum of Human Genome Variation using Linked-Reads

Patrick Marks, Sarah Garcia, Álvaro Martínez Barrio, Kamila Belhocine, Jorge Bernate, Rajiv Bharadwaj, Keith P. Bjornson, Claudia Catalanotti, Josh Delaney, Adrian N. Fehr, Ian T. Fiddes, Brendan D. Galvin, Haynes Heaton, Jill Herschleb, Christopher M. Hindson, , Deanna M. Church

This paper introduces Linked-Reads as a method to comprehensively analyze genome variation, showing it can detect both small and large variants and reconstruct haplotypes more effectively than short-read sequencing.

Genome Research · Apr 1, 2019Peer-reviewedGenomics

Massively parallel digital transcriptional profiling of single cells

Grace X. Y. Zheng, Jessica M. Terry, Phillip Belgrader, Paul Ryvkin, Zachary Bent, Ryan Wilson, Solongo B. Ziraldo, Tobias D. Wheeler, Geoff P. McDermott, Junjie Zhu, Mark Gregory, Joe Shuga, Luz Montesclaros, Jason G. Underwood, Don A. Masquelier, , Jason H. Bielas

8-channel GemCode droplet barcoding captures ∼50% of loaded cells for 3′ mRNA counting, profiling 68k peripheral blood mononuclear cells and calling transplant chimerism from transcript variants.

Nature Communications · Jan 16, 2017Peer-reviewedGenomics✦ In-depth digest

Health and population effects of rare gene knockouts in adult humans with related parents

Vagheesh Narasimhan, Karen Hunt, Dan Mason, Christopher L Baker, Konrad Karczewski, Michael Barnes, Anthony Barnett, Chris Bates, Srikanth Bellary, Nick Bockett, Kristina Giorda, Chris Griffiths, Harry Hemingway, Zhilong Jia, Ann Kelly, , David van Heel

The paper estimates the health effects of rare gene knockouts in adults by analyzing exome sequencing data and health records, finding no significant disease associations.

Science · Apr 22, 2016Peer-reviewedGenomics