Author

Jon M. Sorenson

10X Genomics (United States)ORCID 0000-0002-5301-8306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:clustering· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Claudia Catalanotti· 2 shared Shamoni MaheshwariiD· 2 shared Vijay Kumar· 2 shared Yifeng YiniD· 2 shared Adam Weinstein· 1 shared Andrew D. Price· 1 shared Anthony J. Makarewicz· 1 shared Anuja SatheiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Claudia Catalanotti

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2 papers

Recent·Most cited

Joint single cell DNA-Seq and RNA-Seq of gastric cancer reveals subclonal signatures of genomic instability and gene expression

Noemi Andor, Billy T. Lau, Claudia Catalanotti, Vijay Kumar, Anuja Sathe, Kamila Belhocine, Tobias D. Wheeler, Andrew D. Price, Maengseok Song, Željko Džakula, Jon M. Sorenson, David A. Stafford, Zachary Bent, Laura E. DeMare, Lance Hepler, , Hanlee P. Ji

The paper combines single cell DNA-Seq and RNA-Seq in gastric cancer to reveal subclonal genomic instability and gene expression patterns, showing evidence of tumor evolution.

bioRxiv · Jun 21, 2020 · PreprintGenomics

Resolving sub-clonal heterogeneity within cell-line growths by single cell sequencing genomic DNA

Enrique I. Velazquez-Villarreal, Shamoni Maheshwari, Jon M. Sorenson, Ian T. Fiddes, Vijay Kumar, Yifeng Yin, Michelle G. Webb, Claudia Catalanotti, Mira Grigorova, Paul A. Edwards, John David Carpten, David Wesley Craig

The paper uses single-cell sequencing of genomic DNA to resolve sub-clonal heterogeneity in the COLO829 cell line, identifying four major sub-clones and explaining conflicting bulk sequencing results.

bioRxiv · Sep 5, 2019 · PreprintGenomics