Author

Michael T. Parker

Georgetown University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam J. CloreiD· 1 shared Akiko Iwasaki· 1 shared André Rusch· 1 shared Brett D. Lindenbach· 1 shared Bryan T. GemleriD· 1 shared Caitlin A. D. JaglaiD· 1 shared Corey E. Perez· 1 shared Craig Bartling· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Adam J. CloreORCID

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Author profile →

2 papers

Recent·Most cited

Developing a Standard Definition for Sequences of Concern

Tessa Alexanian, Jacob Beal, Craig Bartling, Jens Berlips, Peter A. Carr, Adam J. Clore, Helena Cozzarini, James Diggans, Yorgo El Moubayed, Kevin M. Esvelt, Kevin Flyangolts, Leonard Newton Foner, Patrick A. Fullerton, Bryan T. Gemler, Caitlin A. D. Jagla, , Nicole E. Wheeler

The paper develops a rubric to define sequences of concern by analyzing test sequences and refining categorization through stakeholder review, reducing disputed categorization by 44.3% for controlled viruses.

Frontiers in Bioengineering and Biotechnology · Jun 4, 2026Peer-reviewedBioinformatics

Innate Immune Priming by cGAS as a Preparatory Countermeasure Against RNA Virus Infection

Michael T. Parker, Smita Gopinath, Corey E. Perez, Melissa M. Linehan, Jason M. Crawford, Akiko Iwasaki, Brett D. Lindenbach

This study shows that cGAS-STING restricts RNA viruses by sensing endogenous DNA ligands, promoting a preparatory immune state even in the absence of viral DNA.

bioRxiv · Oct 3, 2018 · PreprintImmunology