Author

Michal Pikusa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Adriano AguzziiD· 1 shared Alejandro ReyesiD· 1 shared Andrea ArmaniiD· 1 shared Andrea Byrnes· 1 shared Andrew T. Krueger· 1 shared Anna SpinelliiD· 1 shared Ashutosh DhingraiD· 1 shared Britta Knapp· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Adriano AguzziORCID

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Author profile →

2 papers

Recent·Most cited

Specificity and exon target space of splicing modifying compounds

Felina Lenkeit, Judith Knehr, Marc Altorfer, Andrea Byrnes, Wenjing Li, Jack Hsiao, Connie Wu, Priti V. Gaitonde, Philip R. Skaanderup, Steve Mullin, Elizaveta M. Solovyeva, Michal Pikusa, Andrew T. Krueger, Johannes Ottl, Caroline Gubser Keller, , Alejandro Reyes

This study investigates the specificity of splicing modulators by analyzing their interactions with RNA structures and demonstrates reprogramming of their specificity through genetic manipulation of the spliceosome.

DOAJ (DOAJ: Directory of Open Access Journals) · Jul 1, 2026Peer-reviewedMolecular Biology

Robust and Versatile Arrayed Libraries for Human Genome-Wide CRISPR Activation, Deletion and Silencing

Jiang‐An Yin, Lukas D. Frick, Manuel C. Scheidmann, Tingting Liu, Chiara Trevisan, Ashutosh Dhingra, Anna Spinelli, Yancheng Wu, Longping Yao, Dalila Laura Vena, Britta Knapp, Elena De Cecco, Kathi Ging, Andrea Armani, Edward J. Oakeley, , Adriano Aguzzi

The paper constructs genome-wide CRISPR libraries for gene ablation, activation, and silencing with high efficacy and reports novel gene regulators and modifiers.

bioRxiv · May 25, 2022 · PreprintGenomics