Author

Ming Zi Xu

BC Cancer – Victoria

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:spatial domain detection· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1

Frequent Co-Authors

Katy MilneiD· 3 shared Ariane BrassardiD· 2 shared Betty GianniasiD· 2 shared Brad H. NelsoniD· 2 shared France BourdeauiD· 2 shared Iqraa Dhoparee‐DoomahiD· 2 shared Jonathan Cools‐LartigueiD· 2 shared Jonathan Spicer· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Katy MilneORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Engineered T cells controlled by granulocyte colony-stimulating factor eradicate murine melanoma without lymphodepletion or interleukin-2

Sam C Preshaw, Megan Fuller, Cameron J. Powell, Katy Milne, Kassandra Sewell, Mitchell Brady Adamson, Alexi S. Pearson-Lund, Marco Joly, Sydney Goodwin, Niloufar Shakerian, Natalie J.S. Taylor, Ming Zi Xu, Danielle Klassen, Taise Bryce, Julian C Smazynski, , Brad H. Nelson

This study engineers T cells to respond to G-CSF instead of IL-2, enabling effective melanoma treatment without lymphodepletion or IL-2.

bioRxiv · Oct 28, 2026 · PreprintImmunology

RORγ Inverse Agonism Redirects Tumour-Conditioned Emergency Myelopoiesis and Attenuates Established Tumour Progression

Iqraa Dhoparee‐Doomah, Kim Ma, Ariane Brassard, Sabrina Leo, Shayan Hajhashemi, Yichen Li, Katy Milne, Ming Zi Xu, Qian Qiu, Manal Al Dow, Ahmed Fouda, France Bourdeau, Benjamin Gordon, Betty Giannias, Brad H Nelson, , Jonathan Cools‐Lartigue

This study shows that RORγ inverse agonism reduces tumor progression by altering myeloid cell organization and immune responses in gastroesophageal adenocarcinoma.

bioRxiv · Oct 7, 2026 · PreprintCancer Biology

A Measurable Systemic Immune Phenotype Links Circulating Myeloid Dysfunction to Tumour Spatial Organization in Gastroesophageal Adenocarcinoma

Iqraa Dhoparee‐Doomah, Yichen Li, Manal Al Dow, Shayan Hajhashemi, Ariane Brassard, Nissim Benizri, Sabrina Leo, Katy Milne, Ming Zi Xu, Qian Qiu, Brad H. Nelson, Pierre-Olivier Fiset, Betty Giannias, France Bourdeau, Jonathan Spicer, , Jonathan Cools‐Lartigue

This study links circulating myeloid dysfunction, measured by cNLR, to tumour spatial organization in GEA through multiscale analyses of immune function, single-cell transcriptomics, and spatial myeloid organization.

bioRxiv · Sep 18, 2026 · PreprintCancer Biology