Integrating mass spectrometry with Nanopore direct RNA sequencing for de novo modification profiling of bacteriophage MS2
Joshua D. Jones, Neda Ghohabi Esfahani, Calvin L.C. Goemann, Tanner Wiegand, Artem A. Nemudryi, Minli Ruan, Xiaoyan Li, Mehmet Tardu, Robert T. Kennedy, Blake Wiedenheft, Miten Jain, Kristin S. Koutmou
The paper profiles RNA modifications in MS2 bacteriophage using LC-MS/MS and Nanopore DRS, finding {Psi} as the predominant modification.
bioRxiv · Jun 2, 2026 · PreprintBiochemistry