Author

Mohammad Lutful Kabir

Kent State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Hamza BalciiD· 4 shared Janan Alfehaid· 3 shared Sajad A. ShiekhiD· 3 shared Sineth G. KodikaraiD· 3 shared Mohammed Enamul HoqueiD· 2 shared Soumitra BasuiD· 2 shared John J. PortmaniD· 1 shared Kazuo Nagasawa· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersBiophysics

Hamza BalciORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Accessibility of Telomeric Overhangs to Stabilizing Small-Molecule Ligands

Janan Alfehaid, Vidsara Surasinghe, Sineth G. Kodikara, Mohammad Lutful Kabir, Sajad A. Shiekh, Masayuki Tera, Kazuo Nagasawa, John J. Portman, Hamza Balci

This study investigates how telomeric overhang architecture affects small-molecule ligand accessibility by analyzing binding stoichiometry and cooperativity in G-quadruplex structures.

Nucleic Acids Research · Jun 18, 2026Peer-reviewedBiophysics

Combining the CRISPR Activation and Interference Capabilities Using dCas9 and G-Quadruplex Structures

Mohammad Lutful Kabir, Sineth G. Kodikara, Mohammed Enamul Hoque, Sajad A. Shiekh, Janan Alfehaid, Soumitra Basu, Hamza Balci

This study shows that CRISPR-dCas9 targeting G-quadruplex structures in the c-Myc promoter can activate or suppress gene expression, with dual targeting achieving significant reductions in mRNA and protein levels.

NAR Molecular Medicine · Jan 1, 2025Peer-reviewedMolecular Biology

Reusable Microfluidic Chambers for Single-Molecule Microscopy

Janan Alfehaid, Sineth G. Kodikara, Tuqa Alhajri, Mohammad Lutful Kabir, Hamza Balci

This paper demonstrates a method to reset and reuse single-molecule microfluidic chambers using photocleavable biotin and UV light, enabling at least 10 cycles without surface degradation.

ACS Applied Materials & Interfaces · Oct 10, 2024Peer-reviewedBiophysics

Stalling of Transcription by Putative G-quadruplex Sequences and CRISPR-dCas9

Mohammed Enamul Hoque, Mohammad Lutful Kabir, Sajad A. Shiekh, Hamza Balci, Soumitra Basu

The paper investigates how CRISPR-dCas9 and G-quadruplex sequences affect transcription by studying their impact on RNA polymerase elongation in specific promoter regions.

bioRxiv · Mar 17, 2024 · PreprintMolecular Biology