Cell BiologyiSciencePeer-reviewed
Mechanical control of the splicing factor PTBP1 regulates extracellular matrix stiffness-induced cell proliferation and mechanomemory
Pei-Li Tseng, Weiwei Sun, Ahmed Salem…·Kai S. Erdmann
This study identifies PTBP1 as a mechanotransducer that regulates cell proliferation and mechanomemory through mechanosensitive splicing of Numb in response to extracellular matrix stiffness.
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