Author
Innovative Genomics Institute
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Luis E. Valentin-Alvarado, Peter H. Yoon, Santiago C. Lopez…·Jennifer A. Doudna
The paper identifies a bacterial immune pathway where tRNA cleavage generates second messengers that trigger cell death via RNA-guided nuclease activity.
Zehan Zhou, Iren Saffarian-Deemyad, Honglue Shi…·Jennifer A. Doudna
Ymu1 TnpB unwinds DNA via a long-lived partially unwound intermediate before a rarely stable open state; the WFR triple variant stabilizes both, boosting plant editing.
Peter H. Yoon, Kenneth J. Loi, Zeyuan Terry Zhang…·Jennifer A. Doudna
The paper identifies VIPR systems, which use noncontiguous RNA codes for DNA recognition, suggesting an ancient origin of adaptive immunity through viral interactions.