Author

N. A. Rohner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

H. A. von Recum· 2 shared A. B. Desai· 1 shared A. B. Dogan· 1 shared A. H. K. Ashkezari· 1 shared A. M. Rosado· 1 shared B. Kinney· 1 shared C. Ge· 1 shared C. Zhu· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

H. A. von Recum

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Author profile →

3 papers

Recent·Most cited

Tumor microenvironments impair T cell receptor affinity and function

Z. Yuan, M. J. O'Melia, K. Li, J. Lyu, A. M. Rosado, V. E. Watson, A. H. K. Ashkezari, F. Zhou, V. Kansal, B. Kinney, S. Travaglino, L. O. Doudy, R. K. Noel, S. N. Lucas, S. L. Kong, , C. Zhu

This study shows that CD8+ T cells in the tumor microenvironment have reduced TCR-pMHC affinity and function, impairing their anti-tumor activity.

bioRxiv · Sep 11, 2022 · PreprintImmunology

Polymer microparticles prolong delivery of the 15-PGDH inhibitor SW033291

A. B. Dogan, N. A. Rohner, J. N. P. Smith, J. A. Kilgore, N. S. Williams, S. D. Markowitz, H. A. von Recum, A. B. Desai

This paper develops a sustained release platform using β-CD microparticles to extend the delivery of the 15-PGDH inhibitor SW033291 beyond one week.

bioRxiv · Aug 15, 2021Bioengineering

Affinity-based polymers provide long-term immunotherapeutic drug delivery across particle size ranges optimal for macrophage targeting

N. A. Rohner, L. Purdue, H. A. von Recum

This study shows that cyclodextrin polymers enable long-term drug delivery with size-tunable cellular uptake and size-independent release of lenalidomide for macrophage targeting.

bioRxiv · Oct 13, 2019Bioengineering