Author

N. A. Speck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Battle· 1 shared A. E. Baxter· 1 shared A. Gagne· 1 shared A. R. Greenplate· 1 shared C. Nations· 1 shared C. S. Thom· 1 shared D. French· 1 shared E. Arai· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. Battle

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tropomyosin 1 deficiency facilitates cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis

M. Wilken, G. Fonar, C. Nations, G. Pavani, J. Gariffalou, J. Tober, L. F. Bennett, J. A. Maguire, A. Gagne, N. Okoli, P. Gadue, S. Chou, N. A. Speck, D. French, C. S. Thom

This study shows TPM1 deficiency promotes cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis in both human and mouse models.

bioRxiv · Sep 1, 2023Cell Biology

In vivo CRISPR screening identifies Fli1 as a transcriptional safeguard that restrains effector CD8 T cell differentiation during infection and cancer

Z. Chen, E. Arai, O. Khan, Z. Zhang, S. F. Ngiow, Y. He, H. Huang, S. Manne, Z. Cao, A. E. Baxter, Z. Cai, E. Freilich, M. A. Ali, J. R. Giles, J. E. Wu, , J. Shi

The paper identifies Fli1 as a transcriptional regulator that limits effector CD8 T cell differentiation during infection and cancer, showing its deletion enhances TEFF responses and immunity.

bioRxiv · May 20, 2020 · PreprintImmunology