Author

N. Alvinez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

A. D. Tran· 1 shared A. G. Parrish· 1 shared A. S. Yamashita· 1 shared B. N. Gessesse· 1 shared D. C. Quist· 1 shared D. K. Kumasaka· 1 shared D. Rudoy· 1 shared E. C. Holland· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. D. Tran

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.

S. Schmid, Z. R. Russell, A. S. Yamashita, M. E. West, A. G. Parrish, J. Walker, D. Rudoy, J. Z. Yan, D. C. Quist, B. N. Gessesse, N. Alvinez, P. J. Cimino, D. K. Kumasaka, R. E. Parchment, E. C. Holland, F. Szulzewsky

This study shows ERK signaling promotes resistance to TRK inhibitors in NTRK fusion-driven glioma mouse models and suggests MEK inhibition as a potential combination therapy.

bioRxiv · Mar 13, 2024Cancer Biology

Generation of anti-tumor chimeric antigen receptors incorporating T cell signaling motifs

L. Balagopalan, T. Moreno, H. Qin, J. Yi, K. M. M. McIntire, N. Alvinez, S. Pallikkuth, M. E. Lee, H. Yamane, A. D. Tran, P. Youkharibache, R. E. Cachau, N. Taylor, L. E. Samelson

This paper develops novel Chimeric Adapter Proteins (CAPs) that enhance T cell signaling and anti-tumor efficacy compared to conventional CAR-T cells.

bioRxiv · Dec 25, 2022 · PreprintImmunology