Author

M. E. West

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

A. G. Parrish· 1 shared A. S. Yamashita· 1 shared B. N. Gessesse· 1 shared D. C. Quist· 1 shared D. K. Kumasaka· 1 shared D. Rudoy· 1 shared E. C. Holland· 1 shared F. Szulzewsky· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. G. Parrish

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2 papers

Recent·Most cited

ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.

S. Schmid, Z. R. Russell, A. S. Yamashita, M. E. West, A. G. Parrish, J. Walker, D. Rudoy, J. Z. Yan, D. C. Quist, B. N. Gessesse, N. Alvinez, P. J. Cimino, D. K. Kumasaka, R. E. Parchment, E. C. Holland, F. Szulzewsky

This study shows ERK signaling promotes resistance to TRK inhibitors in NTRK fusion-driven glioma mouse models and suggests MEK inhibition as a potential combination therapy.

bioRxiv · Mar 13, 2024Cancer Biology

Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains

S. Wong, M. E. West, G. J. Morgan

This study investigates the kinetic behavior of antibody light chain variable domain aggregation, finding non-linear concentration dependence and multiple aggregation pathways.

bioRxiv · Aug 28, 2023Biochemistry