Author

N. Bovenschen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. D. Meringa· 1 shared A. Slomp· 1 shared D. Kaiserman· 1 shared D. M. Bosma· 1 shared D. Rockx-Brouwer· 1 shared G. Salvesen· 1 shared J. Kuball· 1 shared J. Kulbacka· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. D. Meringa

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Engineering BCMA CAR T cells for myeloma-targeted cargo delivery

T. Kimman, M. Cuenca, A. Slomp, R. G. Tieland, D. Rockx-Brouwer, S. Heijhuurs, A. D. Meringa, W. Boschloo, D. M. Bosma, S. Kroos, V. lo Presti, S. Nierkens, N. Bovenschen, J. Kuball, M. C. Minnema, , V. Peperzak

This paper develops BCMA CAR T cells with a granzyme B-NOXA fusion to enhance apoptosis in multiple myeloma cells, improving killing efficacy in vitro and in xenograft models.

bioRxiv · Feb 14, 2024 · PreprintImmunology

Noninvasive optical detection of Granzyme B from natural killer cells using enzyme-activated fluorogenic probes

T. Janiszewski, S. Kolt, D. Kaiserman, S. S. Snipas, S. Li, J. Kulbacka, J. Saczko, N. Bovenschen, G. Salvesen, M. Drag, P. Bird, P. Kasperkiewicz

This study develops a fluorogenic probe for detecting Granzyme B activity in natural killer cells and demonstrates its use in analyzing GrB localization and function in cytotoxic cells.

bioRxiv · Dec 16, 2019Biochemistry