Author

N. C. Gianneschi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:protein folding & dynamics· 1 Organism:rat· 1

Frequent Co-Authors

C. Luo· 2 shared H. Sullivan· 2 shared J. Korpanty· 2 shared K. Worthington· 2 shared Y. Liang· 2 shared G. Jacoby· 1 shared G. Koren· 1 shared H. Shinar· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

C. Luo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inflammation-Responsive Micellar Nanoparticles from Degradable Polyphosphoramidates for Targeted Delivery to Myocardial Infarction

Y. Liang, H. Sullivan, K. Carrow, J. Korpanty, K. Worthington, C. Luo, K. L. Christman, N. C. Gianneschi

This paper develops biodegradable micellar nanoparticles responsive to inflammation, showing targeted accumulation in myocardial infarction sites in rats.

Journal of the American Chemical Society · May 15, 2023Peer-reviewedBiochemistry

Self-Assembly of Tunable Intrinsically DisorderedPeptide Amphiphiles

T. Ehm, H. Shinar, G. Jacoby, S. Meir, G. Koren, M. Segal Asher, J. Korpanty, M. P. Thompson, N. C. Gianneschi, M. M. Kozlov, S. E. Azoulay-Ginsbur, R. Amir, J. O. Raedler, R. Beck

This study investigates how sequence variations in IDPAs affect their self-assembly structures and phase transitions, showing that single amino acid mutations can tune mesophase behavior and enable enzymatic activation.

bioRxiv · Oct 28, 2022Biophysics

Enzyme-Responsive Nanoparticles for the Targeted Delivery of an MMP Inhibitor to the Heart post Myocardial Infarction

H. Sullivan, Y. Liang, K. Worthington, C. Luo, N. C. Gianneschi, K. Christman

This paper develops enzyme-responsive nanoparticles that deliver an MMP inhibitor to the heart after myocardial infarction, showing targeted retention and controlled drug release.

bioRxiv · Mar 7, 2022 · PreprintBioengineering