Conversion of methionine biosynthesis in E. coli from trans- to direct-sulfurylation enhances extracellular methionine levels
N. Gruzdev, Y. Hacham, H. Haviv, I. Stern, M. Gabay, I. Bloch, R. Amir, M. Gal, I. Yadid
This paper enhances L-methionine production in E. coli by replacing the trans-sulfurylation pathway with direct-sulfurylation, achieving up to 160-fold higher extracellular methionine levels.
bioRxiv · Mar 28, 2023Biochemistry