STING activation promotes robust immune response and NK cell-mediated tumor regression in glioblastoma models
G. Berger, E. H. Knelson, J. L. Jimenez-Macias, M. O. Nowicki, S. Han, P. H. Lizotte, K. Adu-Berchie, A. Stafford, N. Dimitrikakis, E. A. Chiocca, D. J. Mooney, D. A. Barbie, S. E. Lawler
This study shows that STING activation in glioblastoma models enhances immune responses and NK cell-mediated tumor regression, with long-term survival benefits in murine models.
bioRxiv · Feb 28, 2022 · PreprintCancer Biology