Author

D. A. Barbie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

A. H. Sabet· 1 shared A. Stafford· 1 shared A. Vajdi· 1 shared C. M. Rudin· 1 shared D. J. Mooney· 1 shared E. A. Chiocca· 1 shared E. H. Knelson· 1 shared E. Walton· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. H. Sabet

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

STING activation promotes robust immune response and NK cell-mediated tumor regression in glioblastoma models

G. Berger, E. H. Knelson, J. L. Jimenez-Macias, M. O. Nowicki, S. Han, P. H. Lizotte, K. Adu-Berchie, A. Stafford, N. Dimitrikakis, E. A. Chiocca, D. J. Mooney, D. A. Barbie, S. E. Lawler

This study shows that STING activation in glioblastoma models enhances immune responses and NK cell-mediated tumor regression, with long-term survival benefits in murine models.

bioRxiv · Feb 28, 2022 · PreprintCancer Biology

Regulation of Neuroendocrine Plasticity by the RNA-Binding Protein ZFP36L1

H.-Y. Chen, Y. T. Durmaz, Y. Li, A. H. Sabet, A. Vajdi, T. Denize, E. Walton, J. G. Doench, N. R. Mahadevan, J. A. Losman, D. A. Barbie, M. Y. Tolstorukov, C. M. Rudin, T. Sen, S. Signoretti, M. Oser

This study identifies ZFP36L1 as an LSD1 target gene that regulates neuroendocrine plasticity in SCLC by destabilizing mRNAs of lineage transcription factors.

bioRxiv · Oct 22, 2021Cancer Biology

Engineering the Immune Adaptor Protein STING as a Biologic

X. Sun, Y. Ni, Y. He, M. Yang, T. Tani, S. Kitajima, D. A. Barbie, J. Li

This study engineers the STING protein as a delivery system to enhance CDN delivery and restore STING signaling in cancer cells.

bioRxiv · Feb 18, 2021 · PreprintBioengineering